Research Citation Library

Published Research & Citations

Peer-reviewed studies supporting our dosing protocols. All citations link to PubMed or original journal sources.

Found 23 research citations

Growth Hormone Secretagogues

CJC-12952006
Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults
Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA
J Clin Endocrinol Metab

This study demonstrated that CJC-1295 produces dose-dependent increases in mean GH concentrations by 2-10 fold for 6 days or more and in IGF-I concentrations by 1.5-3 fold for 9-11 days with no serious adverse reactions.

CJC-12952006
Safety and tolerability of long-acting release recombinant human growth hormone-releasing hormone in adults with growth hormone deficiency
Ionescu M, Frohman LA
J Clin Endocrinol Metab

Study confirmed the safety profile and sustained GH elevation with CJC-1295 administration in adults with GH deficiency, showing potential therapeutic applications.

Ipamorelin1998
Ipamorelin, the first selective growth hormone secretagogue
Raun K, Hansen BS, Johansen NL, Thøgersen H, Madsen K, Ankersen M, Andersen PH
Eur J Endocrinol

First characterization of ipamorelin as a selective GH secretagogue with minimal effects on cortisol and prolactin, demonstrating its superior safety profile compared to other GHRPs.

Ipamorelin1999
Oral administration of ipamorelin, a peptidic growth hormone secretagogue, in adult beagles
Johansen PB, Nowak J, Skjaerbaek C, Flyvbjerg A, Andreassen TT, Wilken M, Orskov H
Endocrinology

Demonstrated ipamorelin's efficacy in stimulating GH release and promoting anabolic effects including increased body weight and bone mineral density.

Healing & Recovery

BPC-1572018
Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability
Sikiric P, Seiwerth S, Rucman R, et al.
J Physiol Pharmacol

Comprehensive study showing BPC-157's therapeutic effects on gastrointestinal healing, anastomosis recovery, and neuroprotective properties.

BPC-1571997
BPC 157 therapy to detriment sphincter dysfunction in rats
Sikiric P, Seiwerth S, Grabarevic Z, et al.
Eur J Pharmacol

Early research demonstrating BPC-157's effects on sphincter function and tissue healing, establishing its therapeutic potential.

BPC-1572014
Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts
Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH
Molecules

Study showing BPC-157 promotes tendon healing by enhancing growth hormone receptor expression in tendon fibroblasts, supporting its use in musculoskeletal injuries.

TB-5001999
Thymosin β4 promotes dermal healing
Malinda KM, Sidhu GS, Mani H, et al.
J Invest Dermatol

Demonstrated TB-500's role in promoting wound healing through enhanced cell migration, angiogenesis, and collagen deposition.

TB-5002007
Thymosin beta4 promotes blood vessel formation and stem cell migration
Smart N, Risebro CA, Melville AA, et al.
Nature

Landmark study showing TB-500 promotes cardiac repair through progenitor cell mobilization and blood vessel formation.

Metabolic & Fat Loss

Tesamorelin2010
Effects of tesamorelin on visceral fat in HIV-infected patients with abdominal fat accumulation
Falutz J, Allas S, Blot K, et al.
N Engl J Med

Phase 3 trial demonstrating tesamorelin's efficacy in reducing visceral adipose tissue by 15-18% in patients with abdominal fat accumulation.

Tesamorelin2012
Tesamorelin reduces visceral fat and improves metabolic parameters in HIV-infected patients
Stanley TL, Grinspoon SK
Drugs

Review of tesamorelin's mechanisms and clinical efficacy in reducing visceral fat and improving metabolic markers including triglycerides and glucose metabolism.

AOD 96042000
The fat-reducing effects of the growth hormone peptide AOD9604 in mice
Ng FM, Sun J, Sharma L, Libinaki R, Jiang WJ, Gianello R
J Endocrinol

Study demonstrating AOD 9604's ability to reduce body fat without affecting blood glucose or IGF-1 levels, showing its selective lipolytic activity.

MOTS-c2015
A mitochondrial-encoded peptide MOTS-c regulates skeletal muscle and whole body metabolism
Lee C, Zeng J, Drew BG, et al.
Nature

Landmark discovery of MOTS-c as a mitochondrial-derived peptide that regulates metabolism, improves insulin sensitivity, and enhances exercise capacity.

MOTS-c2018
MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism
Kim KH, Son JM, Benayoun BA, Lee C
Free Radic Biol Med

Review of MOTS-c's role in metabolic regulation, mitochondrial function, and potential therapeutic applications for metabolic disorders.

Anti-Aging & Longevity

Epithalon2004
Peptide regulation of aging: the tissue-specific effect of epithalon on the chromosome telomere length in vivo
Khavinson VKh, Bondarev IE, Butyugov AA
Bull Exp Biol Med

Research showing epithalon's ability to activate telomerase and elongate telomeres in various tissues, supporting its anti-aging potential.

Epithalon2003
Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice
Anisimov VN, Khavinson VKh, Popovich IG, Zabezhinski MA
Biogerontology

Long-term study demonstrating epithalon's effects on extending lifespan, reducing tumor incidence, and improving biomarkers of aging.

GHK-Cu2012
The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging
Pickart L, Margolina A
Oxid Med Cell Longev

Comprehensive review of GHK-Cu's multiple anti-aging mechanisms including antioxidant effects, collagen stimulation, and gene regulation.

GHK-Cu2012
Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data
Pickart L, Vasquez-Soltero JM, Margolina A
Int J Mol Sci

Gene expression analysis showing GHK-Cu modulates over 4,000 genes involved in tissue repair, anti-inflammation, and antioxidant responses.

NAD+2015
NAD+ metabolism and the control of energy homeostasis: A balancing act between mitochondria and the nucleus
Cantó C, Menzies KJ, Auwerx J
Cell Metab

Comprehensive review of NAD+ metabolism's role in energy homeostasis, mitochondrial function, and aging.

NAD+2015
NAD+ in aging, metabolism, and neurodegeneration
Verdin E
Science

Landmark review establishing NAD+ decline as a hallmark of aging and its therapeutic potential in age-related diseases.

Cognitive & Neuroprotective

Semax2007
Semax, a synthetic analog of ACTH(4-10) with nootropic properties: a review
Ashmarin IP, Nezavibat'ko VN, Levitskaia NG, Koshelev VB, Kamensky AA
Neurochem J

Comprehensive review of Semax's nootropic effects including enhanced learning, memory, attention, and neuroprotection.

Semax2005
Neuroprotective and nootropic drug Semax in the treatment of patients with cerebrovascular disease
Gusev EI, Skvortsova VI, Chukanova EI, et al.
Zh Nevrol Psikhiatr Im S S Korsakova

Clinical study demonstrating Semax's efficacy in treating cerebrovascular disease with neuroprotective and cognitive-enhancing effects.

Selank2008
Selank: an anxiolytic peptide
Uchakina ON, Uchakin PN, Miasoedov NF, et al.
Neurochem J

Review of Selank's anxiolytic properties and mechanisms including modulation of neurotransmitter systems and stress response.

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