Selank
Nootropic peptide for cognitive enhancement and anxiety research.
Selank is a synthetic heptapeptide derived from the naturally occurring immunomodulatory peptide tuftsin, enhanced with a sequence designed for improved stability and bioavailability. Developed through Russian research programs, it is primarily investigated for its unique combination of anxiolytic, nootropic, and immunomodulatory properties. Unlike traditional anxiolytics, Selank demonstrates anti-anxiety effects without sedation, addiction potential, or cognitive impairment.
- •Investigates non-sedating anxiolytic mechanisms.
- •Supports research into cognitive enhancement and neuroplasticity.
- •Modulates multiple central neurotransmitter systems (serotonin, GABA, dopamine).
- •Provides insights into peptide-based immunomodulation via its tuftsin-derived sequence.
- •Valuable for studies on stress resilience and adaptation models.
- •Useful for developing non-benzodiazepine neuropsychiatric interventions.
Selank exerts its effects through complex, interconnected modulation of both neural and immune systems. It influences serotonergic neurotransmission by affecting serotonin metabolism and receptor expression, which underpins its mood-regulating and anxiolytic properties. While not directly binding to GABA receptors, the peptide modulates GABAergic system activity and levels through indirect mechanisms. Furthermore, Selank affects dopaminergic pathways, contributing to its observed effects on focus and motivation. The peptide supports neuroplasticity and cognitive function by modulating the expression of neurotrophic factors, including Brain-Derived Neurotrophic Factor (BDNF). Its tuftsin-derived sequence confers immunomodulatory properties, specifically influencing cytokine production and immune cell activity to help balance pro-inflammatory and anti-inflammatory responses. This multi-systemic action allows researchers to study alternative molecular pathways for managing anxiety and cognitive deficits without the limitations associated with traditional pharmacological agents.
Selank is extensively utilized in research focused on anxiety disorder mechanisms, stress adaptation, and the development of novel nootropic agents. Its application extends to investigations into neurotransmitter system modulation, particularly exploring the indirect effects on GABA and serotonin pathways. Researchers also employ Selank to study the interplay between the nervous and immune systems, leveraging its immunomodulatory properties in stress models. Specific areas of study include BDNF upregulation, learning and memory enhancement, and the development of peptide-based interventions for neuropsychiatric conditions.
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Research Use Only
This product is sold strictly for research purposes only. It is not approved by the FDA for human consumption or medical use. Intended for laboratory and research applications by qualified researchers and institutions only.