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BPC-157 + TB-500 Blend

BPC-157 + TB-500 Blend

R 220.00Out of Stock
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Description

GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic hexapeptide belonging to the growth hormone secretagogue family of research compounds. It functions as a potent stimulator of growth hormone (GH) release from the anterior pituitary gland. This compound provides a valuable tool for investigating the growth hormone axis, metabolic regulation, and age-related changes in GH secretion.

Key Benefits
Research applications and potential benefits
  • Potent, dose-dependent stimulation of GH release for precise protocols.
  • Operates via the distinct ghrelin receptor (GHS-R1a) pathway.
  • Minimal impact on cortisol and prolactin compared to related secretagogues.
  • Supports investigation into metabolic regulation and energy homeostasis.
  • Valuable for studying age-related GH decline (somatopause).
  • Promotes downstream IGF-1 production via GH stimulation.
  • Useful for research into body composition and tissue repair models.
  • Demonstrates synergistic effects when combined with GHRH analogs.
Mechanism of Action
How this peptide works

GHRP-2 exerts its effects primarily through the activation of the growth hormone secretagogue receptor (GHS-R1a), which is also known as the ghrelin receptor. This receptor is located on somatotroph cells within the anterior pituitary gland. Binding to GHS-R1a triggers intracellular calcium mobilization and subsequent activation of protein kinase C pathways, leading directly to the release of stored growth hormone. Unlike Growth Hormone Releasing Hormone (GHRH), which primarily increases GH synthesis, GHRP-2 focuses on releasing existing GH reserves. The peptide exhibits synergistic activity with endogenous GHRH, significantly amplifying the magnitude of GH pulses when both signals are present. Furthermore, GHRP-2 stimulates appetite through hypothalamic ghrelin receptor activation, facilitating research into energy balance and feeding behavior. The resulting GH surge subsequently drives IGF-1 production in the liver and peripheral tissues, initiating the associated anabolic and metabolic cascades.

Research Applications
Areas of scientific research

GHRP-2 is extensively studied in the field of growth hormone physiology, particularly concerning pulsatile GH secretion and age-related decline (somatopause). Its distinct mechanism makes it essential for comparative studies with other secretagogues and GHRH analogs, often used in combination protocols to achieve maximal GH release for research purposes. The compound is applied in models investigating metabolic syndrome, insulin sensitivity, and energy homeostasis due to its dual action on GH release and appetite stimulation. Furthermore, GHRP-2 is valuable in research focused on body composition, muscle mass maintenance, bone density, and the relationship between GH signaling and tissue repair or recovery following injury.

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Research Use Only

This product is sold strictly for research purposes only. It is not approved by the FDA for human consumption or medical use. Intended for laboratory and research applications by qualified researchers and institutions only.

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